Research and Innovation

Improving healthcare for the benefit of patients is at the heart of everything we do. Patients within the Trust have some of the best access and opportunities for new therapies and technologies. The Research and Innovation team work hard to provide such clinical research to develop new treatments and knowledge for better health care, building the evidence for new approaches that are safe and effective.  

Our Annual Report is now ready to view.  Click here for a summary 2021-2022

Our Vision:

“Embed a culture in the organisation that enables every patient, carer and clinician the opportunity to participate in research”

Research does not only make improvements for patients and service users, but also provides opportunities for professional and personal growth. Acting as an investigator on a research study that is of interest to you will only improve this growth and development further.

Should the opportunity of being an investigator be of interest to you, please feel free to have a look at some of the Frequently Asked Questions by Investigators who have previously taken up research at the Trust. 

An investigator could be you. If you are interested in conducting research then the following could be really helpful to start you off.

Before you can begin your project, you will require a number of authorisations in line with the Research Governance Framework.

The Integrated Research Application System (IRAS) is the first requirement for obtaining NHS R&I approval. This system helps to administer the appropriate level of authorisations depending on what a research study looks to investigate, or how it is going to go about researching a topic.

For guidance on how to complete an IRAS form, please visit the IRAS Website. Through an IRAS application, you can also apply approvals the appropriate Research Ethics Committee (RECs). Once the study document has been generated by IRAS, you will need to send this to the R&I office.

Once the subjected checks are satisfied, the R&I office will issue you with a formal letter of approval that has been signed by the Director of R&I. only once all of this has been completed will you be able to begin research at the Trust.

Register for an IRAS Account here

RECs are NHS Research Ethics Committees that safeguard the rights, safety, dignity and well-being of any research participant in order to determine whether a research study is ethical. With approximately one-third of the committee made up of lay members (of a non research profession), Research ethics committees are completely separate to the research sponsor. With over 6000 applications a year being submitted to the 80 research ethics committees in the United Kingdom, expect to hear back from a REC within a maximum of 60 days. Research ethics committees put participants in the centre of their ethical review.

RECs cover a wide range of research topics. These include:

  • Clinical Trials of Investigational Medicinal Products               
  • Research involving Medical Devices     
  • Research involving Prisoners
  • Research involving Adults Lacking Capacity
  • Establishment of Research Tissue Banks
  • Projects funded by the US Department of Health and Human Services
  • Qualitative Research
  • Questionnaire Research
  • Establishment of Research Databases

Applicants for Research Ethics Committees include:

  • Pharmaceutical and medical device companies
  • Healthcare professionals in the NHS
  • Academic researchers, including students
  • Prison health researchers

1. Complete Research Ethics Committee form in IRAS (you must register an account to access this)

Relevant documentation will be requested as per the options selected on IRAS. 

2. Book the application for ethical review 

Telephone your local REC to book a meeting date for discussion of your application. You should be given the name   of an REC, a Reference Number and submission date.

3. Submit your application                

You must submit your application within 4 working days of booking an appointment.

The Proportionate Review Service provides a review for studies which are proven to raise no material ethical issues. The process seen to follow this format is much shorter than a review from a  Research Ethics Committee. A sub-committee is formed in order to attempt to inform the applicant within 14 days of the application being submitted.

Guidance on what consists of a non material ethical issue can be found at the following link.

This provides a ‘No Material Ethical Issues Tool’ (NMEIT) - which acts as a screening tool for the Proportionate Review Service Applications.

NIHR: 

If you are interested in conducting your own research, the National Institute for Health Research (NIHR) can provide you with funding for research studies.  

The NIHR regularly updates the current funding opportunities that it has to offer regarding research studies. All information regarding NIHR’s funding opportunities can be found below; 

Current UKRI Funding Opportunities: 

Current Funding Opportunities

Southern Health: 

Southern Health NHS Foundation Trust’s Research and Innovation are also engaged in looking for opportunities to act as a sponsor within research studies. Recently, Southern Health have acted as sponsor for studies such as L.O.S.E Weight (Liraglutide and the management of Overweight and obesity in people with Schizophrenia: a pilot study).

Innovate UK 

Current Funding

The National Institute of Health Research (NIHR) funds the Research Design Service (RDS) to provide free expert advice and support to researchers (clinicians and academics) who are applying for research funding to national peer reviewed open competitions.

RDS operates in 10 regional centres across England. The local RDS in South Central region has sites in Portsmouth, Southampton and Oxford. RDS advisers are methodologists and can offer a breadth of expertise.

The advice is free and confidential and covers all aspects of developing a grant application, including:

  • research design
  • research methods
  • identifying appropriate funding sources
  • involving patients and the public
  • identifying potential collaborators (academic, clinical, lay)
  • identifying and refining the research questions
  • methodological expertise  covering: medical statistics, health economics, qualitative , mixed methods, clinical trials
  • advice on common pitfalls
  • interpreting feedback from the funding panels

RDS offers support tailored to the needs of the research team and can be contacted as early as necessary. Advice is available at face-to-face meetings, by telephone or email.

You can get in touch with a RDS adviser,

By Email: rds.sc@port.ac.uk

By clicking here to visit the website and filling in a request form

By Phone: 02392 822968

Students who need to conduct a research study as part of their degree course. Below are the stages to go through to get a student research project up and running:

  • Determine whether your study falls under the UK Policy Framework for Research in Health & Social Care:  A handy tool is published on the HRA website. The outcome can be populated with your project title and can be printed off for submission to your University Ethics.
  • Visit the Student research page on the HRA website to familiarise yourself with roles and responsibilities by clicking here  
  • Assuming that the outcome is classified as research, you will need to complete an IRAS application form which will need to be submitted to HRA and if involving patients, to an NHS Research Ethics Committee (REC).  For more information on this process, click here.  Don’t forget to put the names of the NHS organisations in which you wish to undertake your research project into Part C of the IRAS form. 
  • Please also visit the advice on preparation of study documentation by clicking here
  • Following HRA (and REC review if required) you will need to send the pack of documentation to the NHS R&D offices for their capacity and capability review. 
  • On receipt of the NHS organisation email confirming capacity and capability you are good to start recruiting!

All our performance reports can now be found on the National Institute for Health Research's (NIHR) clinical trial performance platform. You can view them by following this link to the platform.

Here at Southern Health NHS Foundation Trust, we are passionate about continuing to improve and revolutionise the way we use clinical data to improve patient outcomes and our services. 

We have implemented a new system called Clinical Record Interactive Search (CRIS), this is an innovative research solution that allows us to safely and securely retrieve data from a Trust’s Electronic Medical Record system and de-identifies it to protect patient identities and then loads it in to a secure database. This will allow us to carry out research for the benefits of patients and society, including clinical audits and service evaluation using information from the Trust’s clinical records.

As well as being valuable in helping with your personal clinical care, the information stored in patient records can be used to help us understand more about the causes of physical and mental illnesses and how best to treat them. This is because they allow us to look at large numbers of people in real life situations. 

This research platform is used by 11 other NHS Mental Health Trusts across the UK to enable research where the results are applicable UK wide. So far we have worked collaboratively with other research Trusts and within the Trust we have also aided pharmacy audits, developed a service evaluation for the Early Intervention in Psychosis (EIP) team, and are working with a service user to develop a research project.

If you would like to find out more about the CRIS Network you can find out here: CRIS Network

If you are happy for your clinical records to be de-identified and included in CRIS you do not need to do anything now. If at any point in the future, you would prefer your de-identified notes to not be included, you can do so by contacting the CRIS Administrator:

Email: cris@southernhealth.nhs.uk

Telephone: 023 8047 5826

CRIS removes or hides any information that can identify you. This is called de-identification. Your name, the name of your carer, your full date of birth, address, postcode and phone numbers is replaced with ‘ZZZZZ’ or truncated to remove chance of identification. This is how the de-identified information would appear:

January 6 2016 ZZZZZ ZZZZZ ZZZZZ ZZZZZ ZZZZZ Dear ZZZZZ Re: Mindfulness Group I am writing to confirm that the next Mindfulness Group will commence on Monday 3 February 2019 for 10 weeks.

If you would like to find out more about CRIS or about taking part in research studies relevant to your health in the Trust, please do contact the CRIS Administrator.

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

African and Caribbean people in the UK are more likely than any other ethnic group to be diagnosed with schizophrenia and other psychoses. However, their experience of mental health services is often poor and they have worse outcomes.  

Culturally-adapted Family Intervention (CaFI) is a multisite research trial in England funded by the National Institute of Health Research Health Technology Assessment Programme (NIHR-HTA). The trial compares treatment as usual to Culturally-adapted Family Intervention delivered in 10 sessions.

Whats Involved

  • Have you been diagnosed with schizophrenia and/or psychosis?
  • Are you a service user of Sub-Saharan African, Caribbean, Black British, or Mixed heritage?
  • We are looking for volunteers to help us test our new “talking therapy” called CaFI (Culturally-adapted Family Intervention) for a research study

Interested?

We are looking for:

  • People of Sub-Saharan African and Caribbean descent, including those who self-identify as ‘Black British’, ‘Black Caribbean’, ‘Black African’, ‘African-Caribbean’ or ‘Mixed’ African/Caribbean
  • At least one parent/ grandparent born in a Sub-Saharan African/ Caribbean country
  • Diagnosis of schizophrenia or related psychoses (ICD F20-29/ DSM-V) (American Psychiatric Association, 2013; World Health Organization, 1992)
  • Receiving treatment via psychiatric inpatient services (acute or rehabilitation), forensic or within community services within a participating NHS Trust
  • 14 years or older in keeping with the age groups served by Early Intervention Services and adult services
  • Ideally have a family member or friend that can take part alongside, but an allocated family support member can be provided

Exclusion criteria

  • Organic brain disorder
  • Cognitive impairment sufficient to impact completion of assessment measures
  • Substance use as primary diagnosis.
  • Currently receiving any form of family intervention

Depression and anxiety are the most common mental health disorders worldwide. In the UK, 1 in 3 people will experience symptoms during their lifetime. The GLAD Study aims to better understand depression and anxiety in order to find effective treatments and improve the lives of people experiencing these disorders.

Whats involved:

There are 4 simple steps to signing up to the GLAD Study:

  1. Register via the website and read the information sheet
  2. Provide consent
  3. Complete a ~30 minute questionnaire to see if you are eligible
  4. Send a saliva DNA sample through the post (IF YOU CURRENTLY FEEL UNWELL PLEASE WAIT TWO WEEKS TO SEND YOUR SALIVA SAMPLE)

Please note: During the questionnaire you will be asked “Did you hear about the GLAD Study through any NHS Trust, GP, talking therapy service, or any other healthcare provider?”. Please select “Yes”.

You will then be asked “Please select which NHS Trust, GP, talking therapy service, or other healthcare provider you heard about the GLAD Study through?”. Please select “Southern Health NHS Foundation Trust”.

You can access the GLAD website here.

This study aims to estimate the prevalence of antibodies against neuronal cell surface targets in patients with psychotic symptoms. This is done by taking a blood sample and analysing it for the presence of these antibodies.

What is involved?

There is a short questionnaire and some blood will be collected. Participants will be given £10 for their time.

Interested?

To take part you must:

  • Be aged between 18-70.
  • Have acute psychosis symptoms: lasting for at least the past two weeks but    no longer than two years.
  • Patients can have a total history of psychosis longer than 2 years, as long as there has been a period of at least six months of remission prior to the current episode. The current episode should be less than 2 years long.

NOTE: You cannot take part if any of the following apply:

  • Any other neurological disorders including multiple sclerosis, epilepsy, cerebrovascular disease, hydrocephalus, traumatic brain injury, meningo-encephalitis, systemic lupus erythematosus, CNS vasculitis.
  • Primary drug induced psychosis
  • Pregnancy.

This study aims to explore the family roles of individuals who have a brother or sister (siblings), and how individuals seek help and cope with difficulties. We hope to better understand the needs of individuals who have a sibling with an Eating Disorder or a different mental health condition, and those who have a sibling with no eating disorder or mental health condition. We hope to do thisthrough exploring siblings experiences of their role within the family, how they cope with difficulties and their attitudes and intentions to seeking help. This research could potentially help professionals to identify individuals who might not seek help but are in need of psychological support.

What is involved?

The study involves completing a set of online questionnaires. These will take approximately 20-30minutes and will ask questions about the way you cope with difficulties, your well-being, how youseek help, your thoughts around seeking help and the roles you take within the family.

Interested?

We are looking for people who:

  • Have a brother or sister
  • Are aged between 16-25
  • Are a UK resident and living in the family home or where the family home is your mainresidence (e.g. you are at university of boarding school during term time)

How can someone take part?If you would like to take part or would like to find out more, you can use this direct link to read more and complete the study questionnaires: https://sotonpsychology.eu.qualtrics.com/jfe/form/SV_aVFACB4qD8rmyvY

Study Lead: Philippa Balfour Trainee Clinical Psychologist

University of Southampton Pb2g11@soton.ac.uk 

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

Alert

*COVID-19 UPDATE:  Screening of Target Genes Asthma is currently paused.*

Previous studies of semaglutide have shown that using semaglutide reduced the risk of cardiovascular events in some people with type 2 diabetes. Semaglutide is already approved in some countries at a lower dose, to treat type 2 diabetes. The SELECT study will examine the effect of semaglutide in people with established cardiovascular disease and obesity or overweight. 

What is involved?

Initially, you will go through a screening process at Moorgreen Hospital to ensure that you meet the criteria for being included in the SELECT study. If you do, the study doctor will explain exactly what is expected of a study participant so you can make an informed decision. Participation in the SELECT study will include:

  • A once-weekly injection of the study medicine, prescribed by the study doctor
  • Attending regular study visits for study-related health checks
  • Regular contact with the study nurse or doctor throughout the study

Interested in taking part?

To take part you must meet the following criteria:

  • Male or female, age ≥ 45 years at the time of signing informed consent
  • Body mass index (BMI) ≥ 27 kg/m2 (overweight)
  • Have established cardiovascular disease – previous heart attack / stroke / PAD (peripheral arterial disease)

NOTE: You cannot take part if you had a TIA (Transient Ischaemic Attack) as opposed to a stroke.

Study Contact: Juliette Meek - Senior Research Nurse

This study is a phase II, randomized, parallel group, multi-center, dose-finding study of subcutaneously administered BI 456906, compared with placebo and open-label semaglutide in patients with type 2 diabetes mellitus who have insufficient glycemic control despite diet, exercise, and metformin treatment.

What is involved?

If you would like to take part you will be invited to come to the clinic for a screen visit. This visit will take 1 hour to complete. If you’re eligible for the study, your participation in the trial will last approximately 23 weeks and require approximately 13 visits to the trial clinic. If you’re in one of the groups receiving the injection twice a week, you will have about 20 visits to the trial clinic. For your time and inconvenience related to taking part in this study, and to take account of any loss of earnings, the sponsor will pay the costs of £30 per visit (plus £10 if you’re assigned to group which need to come to clinic twice per week).

Interested?

To take part you must meet the following criteria:

  • Participant is willing and able to give informed consent for participation in the study;
  • Participant is 18 years to 75 years of age on the day of signing informed consent;
  • Diagnosis of type 2 diabetes mellitus at least 6 months prior to informed consent;
  • Treatment with a stable dose of metformin >=1000mg/day for at least 3 months;
  • BMI 25kg/m2 -50kg/m2;

Study Contact: Qi Zheng

The effect of injectable therapies on health status, quality of life and treatment satisfaction in patients with type 2 diabetes: prospective observational cohort study.

What is Involved?

The study involves three contacts with the research team over a period of six months. These study contacts can either be over the phone or in form of face to face study visits at The Research and Development Department, Moorgreen Hospital, depending on preference. This will involve taking the patients’ medical history, diabetes medications, filling out paper questionnaires about their quality of life and treatment satisfaction and recording their height and weight.

Interested?

Be aged 18+Diagnosis of type 2 diabetes.

Naïve to self – administered SC injectable diabetes therapy at the point of recruitment.

Patients with type 2 diabetes treated with diet or oral medications only, who are planning to start a new oral diabetes medication or injectable diabetes treatments to improve their diabetes control, are invited to take part in this research study.

Study Contact: Liz Houghton

 

 

 

Screening of target genes for polymorphic variation which may alter treatment response for airway treatment targets. The aims of the study are to define the extent of polymorphic variation in genes whose products are, or may be, primary targets for treatment of patients with asthma, and to identify if this genetic variation contributes to disease severity or treatment response.

What is involved?

A 20 - 30 minute appointment which will include:

  • Conducting a breathing test known as spirometry and peak flows.
  • Collecting a blood sample.
  • Asking you a few questions about your asthma and medications you take. 

Interested?

To take part you must meet the following criteria:

  • Have asthma for more than one year.
  • Be prescribed asthma medication.
  • Aged 16 to 60.
  • Of European descent.

NOTE: You cannot take part if:

  • Known highly transmissible or serious blood-borne infection that would render the whole blood and saliva samples a serious biohazard. This includes Hepatitis B, Hepatitis C, and HIV. If the individual gaining consent or performing phlebotomy has any concerns in this regard they should contact one of the study investigators.
  • Anyone unable to comprehend the study and provide informed consent, e.g. insufficient command of English in the absence of someone to adequately interpret.
  • Smoking history of more than ten pack years.
  • Known lung, chest wall, neuromuscular, or cardiac disease or abnormality that would confound symptom scores and Spirometry.

Study Contact: Qi Zheng

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

The aim of this study is to investigate the impact that the COVID-19 outbreak and the current lockdown is having on our behaviour and wellbeing.

If you would like more Information please contact the research team at research@southernhealth.nhs.uk 

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

Cognitive impairments are a core feature of schizophrenia and a major determinant of poor functional outcome. Antipsychotics are the primary medication for schizophrenia, with major effects on the reduction of ‘psychotic’ symptoms but no beneficial effects on cognition. The objectives of this trial is to assess the efficacy in improving cognitive impairment and daily functioning, as well as to assess safety of 26-week treatment of once daily oral treatment with BI 425809 10mg. Also, to assess the efficacy in improving neurocognition, problem solving, performance-based functional capacity and patients’ experience of cognitive impairment.

Inclusion criteria:

  • Male or female patients who are 18-50 years
  • Diagnosis of schizophrenia
    • ​​​​​​​Outpatient
    • No hospitalization within 3 months
  • Functional impairment e.g. following conversation, staying focused
  • Maintained on antipsychotics on current dose (clozapine not allowed)

Get involved
If you meet the inclusion criteria you can refer yourself directly using the details below. 
Clinicians can also refer a patient to the study and can do so via the same route.  
Email: research@southernhealth.nhs.uk
​​​​​​​
Call: 02380 475823

Evaluating the psychotic properties of new measures of responding to distressing voices and other people. This study aims to evaluate the psychometric properties of two new measures of assertive responding to: 1) distressing voices ('auditory hallucinations') and 2) other people. 

Culture Free CBT - Evaluation of a culture free CBT manual

The aim of this study is to assess the feasibility and acceptability of the intervention using the third wave CBT approach with diverse cultures. The objectives of the study are to see if the intervention can reduce (1) symptoms of emotional health problems (2) and, disability. 

A randomised, double blind, placebo controlled parallel group trial of vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis (DFEND). This study aims to explore how the addition of vitamin D supplements to standard treatments can help people recover after having their first episode of psychosis. 

The aim of this survey is to provide information about the health and wellbeing of people with SMI. The two main objectives are: To benchmark current health related behaviours of people with severe mental ill health; and to provide a platform for future research with this population. 

SIREN (Sarscov2 Immunity & Reinfection EvaluatioN):The impact of detectable anti SARS-COV2 antibody on the incidence of COVID-19 in healthcare workers

We are working with Public Health England on an urgent public health Covid-19 (SARS-CoV2) research. The overall aim of the SIREN study is to determine if prior infection on Covid-19 provides future immunity to re-infection. The data collected will also help to inform on the effectiveness of any vaccine administered. 

A study interested in understanding the connections between certain behaviours such as low motivation, negative emotions, difficulties with attention, alcohol use, eating disorders and unusual experiences regarding Mental illness. STRATIFY aims to prove useful in developing better treatments for people who have mental health difficulties. 

This study collects information about treatments in persons who suffer from depression. This study is conducted in a number of countries within the European region to better understand how this condition is treated in these countries. 

The aim of this study is to develop and validate a new outcome measure to assess the construct of personal recovery for carers.  The proposed name of this measure is the Carer Recovery Questionnaire (CRQ).    The study is in several phases, the phase for recruitment at Southern Health is to get carers to test the measure by completing it online.

This study looks at public and patient views on sharing their Health care data with different agencies including national and local NHS Trusts. Its aim is to also explore the possible opt out preferences and when consent to share should be sought.

We would like to learn how many people know about the Arts Therapies and which modality they would chose if given the option. We are asking those with (mental health population) and without (general population) a mental health diagnosis to take part.

Evaluation of the impact of a brief Compassionate Mind Training on Burnout and Self-criticism in MH care professionals.

Burnout is a growing problem among healthcare professionals, and it is a particular problem for mental healthcare professionals, however research is sparse. This study aims to further our understanding of burnout and self-criticism among mental healthcare professionals and explore the effectiveness of brief Compassionate Mind Training in reducing burnout.      

Chief Investigator: Emel Atuk (e.atuk@soton.ac.uk)

Main Supervisor: Dr Margo Ononaiye (m.s.ononaiye@soton.ac.uk)

COPe- E-support for Families and Friends of Individuals affected by Psychosis (EFFIP): A randomised controlled trial of a co-produced online intervention for carers. 

The study aim is to find out if COPe-support works to improve carers’ wellbeing and how well they cope with caring.

The EFFIP Project (E-Support for Families & Friends of Individuals affected by Psychosis) has developed an online resource, called COPe-support (Carers fOr People with Psychosis e-support resource). COPe-support provides peer support, information on psychosis and ways for carers to look after themselves, all online.

This questionnaire hopes to understand the likely causal relationships between the psychological factors measured. Specifically, the aim of the study is to better understand what factors cause dissociation, and whether dissociation might cause psychotic symptoms.

RADAR STUDY- Research into Antipsychotic Discontinuation and Reduction randomised controlled trial. 

The RADAR study assess the benefits and risks of a flexible, supported strategy for antipsychotic dose reduction and possible discontinuation. In particular, it will evaluate effects on social functioning as well as relapse. 

A short questionnaire study aiming to gain insight into the use of self-help apps.

Treatment and Recovery in Psychosis is an evaluation of the benefits of a new care pathway for people who have experienced psychosis. Its research aim is to identify if it is possible to implement a psychosis pathway based on principles of early access to services and interventions and whether it is acceptable to patients and staff. The evaluation will be used to improve the services that people receive.

This study looks at the quality of life of those living with depression currently not responding to medication, newly diagnosed patients and carers (self-identified, could be family or friend) of those with depression.

A study looking at whether self-help books for depression can be helpful.

EMHeP - Efficiency, cost and quality of mental healthcare provision.

A questionnaire study looking at how patients and mental health service professionals value service, quality and outcomes of mental healthcare. A 15 to 20 minute survey. 

If you would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

We support research for a wide range of services, across mental health, memory disorders (MARC),  learning disabilities and community based care. Please click on the below categories to see relevant current studies. 

Diabetes often runs in families; you may have relatives with diabetes yourself or know somebody with diabetes. However, the genes involved are still poorly understood. We hope that by studying the genetic code in people with diabetes we will understand the cause of diabetes and its complications better. Improved knowledge should help us in the treatment and prevention of diabetes. We do hope that in the long term all patients with diabetes will benefit from the knowledge obtained.

An observational study that looks to recruit patients from stroke services such as Rehabilitation Facilities, GP's and TIA clinics, as well as any other service that looks after stroke patients. SIGNUM will also look to recruit patients at risk of stroke, for example those with arterio-venous malformations. The main focus of SIGNUM is to collect genetic and biomarker data linked to data recorded as part of a patient's routine clinical care.

ComPASSION- Healthcare professional awareness of eating disorders in people with Type 1 diabetes

The term ‘diabulimia’ has been used to describe the practice of omitting insulin with the aim of losing weight or preventing weight-gain.  Those affected are at significant risk of diabetes-related complications and premature death alongside the emotional distress associated with the condition.    

This survey will help us to better understand the current level of awareness amongst healthcare professionals of eating disorders in the context of Type 1 diabetes, which will inform the development of services to better support individuals affected by ‘diabulimia’. 

ARTIC PC- Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care

The aim of the ARTIC PC study is to provide evidence to inform the management of chest infections in Primary Care, in children between the ages of six months and thirteen years.       

Liraglutide and the management of Overweight and obesity in people with Schizophrenia: a pilot study. This study will look at the use of a weight loss drug in people with severe mental illness. This is a pilot study to gather data on recruitment, consent, retention, adherence and dropout rates.

A twenty-six week, randomized, open-label, 2-arm parallel group real world pragmatic trial to assess the clinical and health outcomes benefit of transition to Toujeo compared to standard of care insulin, in basal insulin treated patients with uncontrolled type 2 diabetes mellitus, with six-month extension

A study to establish a cohort of people with Type 1 Diabetes and their siblings to further research in this area.

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

There are a number of studies looking into COVID 19

The aim of this study is to investigate the impact that the COVID-19 outbreak and the current lockdown is having on our behaviour and wellbeing.

If you would like more Information please contact the research team at research@southernhealth.nhs.uk 

If you would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

If you would like to get involved or would like more information please contact us at research@southernhealth.nhs.uk 

Please include the study lead or name of the study

Contact us:

Tom Rudd Unit, Moorgreen Hospital West End, Southampton, SO30 3JB

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