Previous studies

Below is a selection of previous studies we have run in the Trust. 

Previous mental health studies

Study now CLOSED 24/4/24

Full Title: What people think about doing physical activity: a questionnaire study


Brief summary

What people think about doing physical activity is a questionnaire study, by a group of psychologist from the University of Oxford. They are looking to understand the way people think about physical activities. They are trying to develop questionnaires to measure thoughts about physical activity and to understand how these thoughts affect their behaviour.

This study they are seeking participants in adult secondary mental health services within the NHS who have a diagnosis of non-affective psychosis.


What is involved?

Online or Paper Questionnaire - There are 2 questionnaire pack. Pack 1 relating to thoughts about exercise and Pack to relating to thoughts about sitting. We are using pack 2 to start with then after 3 months we can get the pack 1 and recruit same patient those who completed pack 2

There is a follow up questionnaire for first 100 participant for both packs.

Participants will be reimbursed £10 for completion of each questionnaire pack


Exclusion criteria

Insufficient English language to understand and completed questionnaires.



To take part you must meet the following criteria:

  • Participant is willing and able to give informed consent for participation in the study.
  • Any gender, aged 16 years or above.
  • Diagnosed with non-affective psychosis (i.e. schizophrenia, schizoaffective disorder, delusional disorder, psychosis not otherwise specified) and/or affective psychosis (i.e. bipolar disorder).
  • Currently attending NHS adult secondary mental health services.

If you would like to take part or want more information please contact the study lead:

Study Contact: Soni Kochuvilayil



Tel: 02380 475943


The aim of this survey is to better understand how to help ethnic minority individuals with schizophrenia and/or psychosis, and their families, by understanding the cultural aspects of care. By doing this, we hope that we can develop better psychological support for ethnic minorities diagnosed with schizophrenia or psychosis. To do this, we need to gather the views of experienced others.


Why take part?

If you choose to take part in this study you will;

  • Contribute to fundamental NHS research that is currently lacking
  • Help us to understand how to assist ethnic minority individuals with psychosis
  • Support underrepresented populations 
  • Contribute to the development of better psychological support
  • Potentially improve quality of life for BAME individuals with psychosis

Who are we looking for

Participants who;

  • Are health care professionals
  • Have some experience of Family Intervention (i.e. Talking Therapy)
  • Have some experience working therapeutically with Black, Asian and Minority Ethnic minority individuals

What is involved?

To take part in this study, you will;

  • Give consent
  • Complete an online 15 minute questionnaire
  • Questionnaire includes demographics, your experience working with BAME groups and your views on the family

To complete the survey, please do so using the below link:

Full Title: Predictors of psychological treatment outcomes for common mental health problems in IAPT service users

Brief summary

Common mental health problems are common and linked to increased morbidity and mortality. Psychological treatments, such as cognitive-behavioural therapy are effective, however, there are mixed findings and overall, appear only effective for half of the treated adults. Identifying predictors of treatment outcomes could have important clinical implications and allow for tailoring of treatments or development of new interventions.

What is involved?

The completion of baseline questionnaires, complemented with treatment related and outcomes measures which are routinely collected by the IAPT services.


To take part you must meet the following criteria:

  • Be aged 18 years or over.
  • Are offered treatment in the IAPT service in step 2 or step 3 of depression and/or an anxiety disorder.
  • Read and understand English at the required level in order to respond to the PIS and the questionnaire.


If you would like to take part or want more information please contact the study lead:

Contact details:

Lizi Graves - 02380 475943


Evaluating the psychotic properties of new measures of responding to distressing voices and other people. This study aims to evaluate the psychometric properties of two new measures of assertive responding to: 1) distressing voices ('auditory hallucinations') and 2) other people. 

Culture Free CBT - Evaluation of a culture free CBT manual

The aim of this study is to assess the feasibility and acceptability of the intervention using the third wave CBT approach with diverse cultures. The objectives of the study are to see if the intervention can reduce (1) symptoms of emotional health problems (2) and, disability. 

A randomised, double blind, placebo controlled parallel group trial of vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis (DFEND). This study aims to explore how the addition of vitamin D supplements to standard treatments can help people recover after having their first episode of psychosis. 

Full Title:


This project aims to obtain the perspectives of service users on the functional and technical requirements of a remotely administered intervention, called DIALOG+. These insights will guide the future development of a prototype DIALOG+ workspace that enables remote communication between clinician and patient. 

What is involved?

A 10–15-minute online questionnaire exploring the opinions and expectations of the functional and technical requirements of a remotely administered intervention called Remote DIALOG+.


To take part you must meet the following criteria:

  • 18 or above
  • Clinical diagnosis of psychosis (ICD-10 F20-29)
  • Experience using secondary mental health services in the last year
  • Capacity to provide informed consent
  • Ability to speak and understand English

The aim of this survey is to provide information about the health and wellbeing of people with SMI. The two main objectives are: To benchmark current health related behaviours of people with severe mental ill health; and to provide a platform for future research with this population. 

SIREN (Sarscov2 Immunity & Reinfection EvaluatioN):The impact of detectable anti SARS-COV2 antibody on the incidence of COVID-19 in healthcare workers

We are working with Public Health England on an urgent public health Covid-19 (SARS-CoV2) research. The overall aim of the SIREN study is to determine if prior infection on Covid-19 provides future immunity to re-infection. The data collected will also help to inform on the effectiveness of any vaccine administered. 

A study interested in understanding the connections between certain behaviours such as low motivation, negative emotions, difficulties with attention, alcohol use, eating disorders and unusual experiences regarding Mental illness. STRATIFY aims to prove useful in developing better treatments for people who have mental health difficulties.

This study collects information about treatments in persons who suffer from depression. This study is conducted in a number of countries within the European region to better understand how this condition is treated in these countries

The aim of this study is to develop and validate a new outcome measure to assess the construct of personal recovery for carers.  The proposed name of this measure is the Carer Recovery Questionnaire (CRQ).    The study is in several phases, the phase for recruitment at Southern Health is to get carers to test the measure by completing it online.

This study looks at public and patient views on sharing their Health care data with different agencies including national and local NHS Trusts. Its aim is to also explore the possible opt out preferences and when consent to share should be sought.

We would like to learn how many people know about the Arts Therapies and which modality they would chose if given the option. We are asking those with (mental health population) and without (general population) a mental health diagnosis to take part.

Evaluation of the impact of a brief Compassionate Mind Training on Burnout and Self-criticism in MH care professionals.

Burnout is a growing problem among healthcare professionals, and it is a particular problem for mental healthcare professionals, however research is sparse. This study aims to further our understanding of burnout and self-criticism among mental healthcare professionals and explore the effectiveness of brief Compassionate Mind Training in reducing burnout.      

Chief Investigator: Emel Atuk (

Main Supervisor: Dr Margo Ononaiye (

COPe- E-support for Families and Friends of Individuals affected by Psychosis (EFFIP): A randomised controlled trial of a co-produced online intervention for carers. 

The study aim is to find out if COPe-support works to improve carers’ wellbeing and how well they cope with caring.

The EFFIP Project (E-Support for Families & Friends of Individuals affected by Psychosis) has developed an online resource, called COPe-support (Carers fOr People with Psychosis e-support resource). COPe-support provides peer support, information on psychosis and ways for carers to look after themselves, all online.

This questionnaire hopes to understand the likely causal relationships between the psychological factors measured. Specifically, the aim of the study is to better understand what factors cause dissociation, and whether dissociation might cause psychotic symptoms.


RADAR STUDY- Research into Antipsychotic Discontinuation and Reduction randomised controlled trial. 

The RADAR study assess the benefits and risks of a flexible, supported strategy for antipsychotic dose reduction and possible discontinuation. In particular, it will evaluate effects on social functioning as well as relapse. 


A short questionnaire study aiming to gain insight into the use of self-help apps.


Treatment and Recovery in Psychosis is an evaluation of the benefits of a new care pathway for people who have experienced psychosis. Its research aim is to identify if it is possible to implement a psychosis pathway based on principles of early access to services and interventions and whether it is acceptable to patients and staff. The evaluation will be used to improve the services that people receive.


This study looks at the quality of life of those living with depression currently not responding to medication, newly diagnosed patients and carers (self-identified, could be family or friend) of those with depression.


A study looking at whether self-help books for depression can be helpful.


EMHeP - Efficiency, cost and quality of mental healthcare provision.

A questionnaire study looking at how patients and mental health service professionals value service, quality and outcomes of mental healthcare. A 15 to 20 minute survey. 

Previous physical health studies

This study is a phase II, randomized, parallel group, multi-center, dose-finding study of subcutaneously administered BI 456906, compared with placebo and open-label semaglutide in patients with type 2 diabetes mellitus who have insufficient glycemic control despite diet, exercise, and metformin treatment.

What is involved?

If you would like to take part you will be invited to come to the clinic for a screen visit. This visit will take 1 hour to complete. If you’re eligible for the study, your participation in the trial will last approximately 23 weeks and require approximately 13 visits to the trial clinic. If you’re in one of the groups receiving the injection twice a week, you will have about 20 visits to the trial clinic. For your time and inconvenience related to taking part in this study, and to take account of any loss of earnings, the sponsor will pay the costs of £30 per visit (plus £10 if you’re assigned to group which need to come to clinic twice per week).


To take part you must meet the following criteria:

  • Participant is willing and able to give informed consent for participation in the study;
  • Participant is 18 years to 75 years of age on the day of signing informed consent;
  • Diagnosis of type 2 diabetes mellitus at least 6 months prior to informed consent;
  • Treatment with a stable dose of metformin >=1000mg/day for at least 3 months;
  • BMI 25kg/m2 -50kg/m2;

Full Title:

The PD Life Study – Exploring the treatment burden in people with Parkinson’s and their caregivers

Brief Summary:

The aim of this study is to understand the experiences of treatment burden and capacity for people with Parkinson’s, and/or those who support or care for someone with Parkinson’s.

We are interested in the effort and day-to-day tasks required to look after the overall health of people who are living with Parkinson’s. Some people will find it easy managing their health, but others may find it more difficult. Some people with Parkinson’s require help from their partner, family member or friends to look after their health. We sometimes refer to this person as a ‘caregiver’.

We may invite them to take part in the study as we are also interested in their experiences of helping to support and care for the health of someone with Parkinson’s. Their participation in this study is through interview with the research team. The results of the study will help us better understand how you look after your health with Parkinson’s.

Full Title:

Strength assessment and strength training in pulmonary rehabilitation: an online survey of services in England

Brief Summary:

A cross-sectional questionnaire-based online survey

Full Title:

Getting the right classification and treatment from diagnosis of diabetes


What is involved?

The purpose of this research is to determine whether blood tests can help us improve treatment by identifying which patients have Type 1 diabetes, and will need very early insulin treatment, and which patients are unlikely to need insulin treatment at diagnosis. These tests include antibodies against the cells that make insulin (often seen in Type 1 diabetes), and a new test which assesses genetic risk of diabetes.



To take part you must meet the following criteria: People were invited to take part in the StartRight study if they were diagnosed with diabetes during the last 12 months, were 18 years of age or over at the time of their diabetes diagnosis.  Taking part in the study may help us discover whether early testing of blood samples can improve diabetes diagnosis and treatment.


Recruitment ended in March 2020 with over 1800 participants consented at 55 UK sites.

Participant follow up at   >3 years post recruitment continues until April 2023.

Full Title:

Nursing shift patterns in acute, community and mental health hospital wards: a feasibility study and survey

Brief Summary:

Nursing shift patterns in acute, community and mental health hospital wards: a feasibility study and survey. 

The aim of this project is to support evidence-based decision making about efficient deployment of nursing staff and care staff on acute, mental health and community hospital wards in England.

Understand how shift work may impact on the experience of work and productivity and preferences and constraints around shift patterns through a survey.

Determine the availability of routinely collected data of shift patterns of the nursing and care workforce and patient outcomes in different hospital settings (acute care, mental health and community).

Explore the feasibility of using routine data to measure associations between shift patterns, workforce characteristics and outcomes including sickness absence.

Screening of target genes for polymorphic variation which may alter treatment response for airway treatment targets. The aims of the study are to define the extent of polymorphic variation in genes whose products are, or may be, primary targets for treatment of patients with asthma, and to identify if this genetic variation contributes to disease severity or treatment response.

What is involved?

A 20 - 30 minute appointment which will include:

  • Conducting a breathing test known as spirometry and peak flows.
  • Collecting a blood sample.
  • Asking you a few questions about your asthma and medications you take. 


To take part you must meet the following criteria:

  • Have asthma for more than one year.
  • Be prescribed asthma medication.
  • Aged 16 to 60.
  • Of European descent.

NOTE: You cannot take part if:

  • Known highly transmissible or serious blood-borne infection that would render the whole blood and saliva samples a serious biohazard. This includes Hepatitis B, Hepatitis C, and HIV. If the individual gaining consent or performing phlebotomy has any concerns in this regard they should contact one of the study investigators.
  • Anyone unable to comprehend the study and provide informed consent, e.g. insufficient command of English in the absence of someone to adequately interpret.
  • Smoking history of more than ten pack years.
  • Known lung, chest wall, neuromuscular, or cardiac disease or abnormality that would confound symptom scores and Spirometry.


Previous studies of semaglutide have shown that using semaglutide reduced the risk of cardiovascular events in some people with type 2 diabetes. Semaglutide is already approved in some countries at a lower dose, to treat type 2 diabetes. The SELECT study will examine the effect of semaglutide in people with established cardiovascular disease and obesity or overweight. 

What is involved?

Initially, you will go through a screening process at Moorgreen Hospital to ensure that you meet the criteria for being included in the SELECT study. If you do, the study doctor will explain exactly what is expected of a study participant so you can make an informed decision. Participation in the SELECT study will include:

  • A once-weekly injection of the study medicine, prescribed by the study doctor
  • Attending regular study visits for study-related health checks
  • Regular contact with the study nurse or doctor throughout the study

Interested in taking part?

To take part you must meet the following criteria:

  • Male or female, age ≥ 45 years at the time of signing informed consent
  • Body mass index (BMI) ≥ 27 kg/m2 (overweight)
  • Have established cardiovascular disease – previous heart attack / stroke / PAD (peripheral arterial disease)

NOTE: You cannot take part if you had a TIA (Transient Ischaemic Attack) as opposed to a stroke.


The effect of injectable therapies on health status, quality of life and treatment satisfaction in patients with type 2 diabetes: prospective observational cohort study.

What is Involved?

The study involves three contacts with the research team over a period of six months. These study contacts can either be over the phone or in form of face to face study visits at The Research and Development Department, Moorgreen Hospital, depending on preference. This will involve taking the patients’ medical history, diabetes medications, filling out paper questionnaires about their quality of life and treatment satisfaction and recording their height and weight.


Be aged 18+Diagnosis of type 2 diabetes.

Naïve to self – administered SC injectable diabetes therapy at the point of recruitment.

Patients with type 2 diabetes treated with diet or oral medications only, who are planning to start a new oral diabetes medication or injectable diabetes treatments to improve their diabetes control, are invited to take part in this research study.

Study Contact: Liz Houghton

Full Title

HypoRESOLVE Understanding the impact Hypoglycaemica has on people living with Diabetes


Brief summary

The purpose of this project is to reduce the burden and consequences of hypoglycaemia in people living with diabetes.  As part of the HypoRESOLVE project we want to understand how hypoglycaemia can affect the day-to-day lives of people living with diabetes. 


What is involved?

You will be asked to complete the survey. The survey contains questions about you and your experiences. 



To take part you must meet the following criteria:

Have diabetes and experience hypoglycaemia 


If you would like to take part or want more information please contact the study lead:

If you are interested in taking part click below to access the survey and find out more details about the research.



If you would like to take part or want more information please contact the study lead:

Study Contact: Kelly Carden or James Watson


Tel: 02380 475943

Full Title

Dealing with Feelings: The Neural Bases of Emotional Processing and Regulation in Bulimia Nervosa


Brief summary

A research study to look at what is happening in the brain while people with and without bulimia nervosa experience and regulate their emotions.


What is involved?

The first part involves filling out an online questionnaire asking about your emotions and eating behaviours amongst other. This should take you about 20-30 minutes.

The second part involves a visit to Bournemouth University which will last around 2.5 hours. There, we will look at your brain activity and you will look a bit like the woman on the picture. This is non-invasive and it does not hurt.

Everyone who takes part will receive £35 plus travel costs to travel to and from Bournemouth.


To take part you must meet the following criteria:

Have a diagnosis of Bulimia Nervosa

have no known suicide ideation

between the age of 18 and 40 


If you would like to take part or want more information please contact the study lead:

Study Contact: Laura Renshaw-Vuillier:  



Title:The Physical and Psychological impact of stroke on carers & relatives


This survey based study seeks to understand the physical and psychological impact of stroke on caregivers. 3 groups were recruited for the study:

Group 1 - stroke caregivers

Group 2 - caregivers for someone who has never had a stroke

Group 3 - anyone (including staff) who indicated that they would become a caregiver if a relative or loved one needed full time care.


Study contact: Vanessa Lucas -


An observational study that looks to recruit patients from stroke services such as Rehabilitation Facilities, GP's and TIA clinics, as well as any other service that looks after stroke patients. SIGNUM will also look to recruit patients at risk of stroke, for example those with arterio-venous malformations. The main focus of SIGNUM is to collect genetic and biomarker data linked to data recorded as part of a patient's routine clinical care.


ComPASSION- Healthcare professional awareness of eating disorders in people with Type 1 diabetes

The term ‘diabulimia’ has been used to describe the practice of omitting insulin with the aim of losing weight or preventing weight-gain.  Those affected are at significant risk of diabetes-related complications and premature death alongside the emotional distress associated with the condition.    

This survey will help us to better understand the current level of awareness amongst healthcare professionals of eating disorders in the context of Type 1 diabetes, which will inform the development of services to better support individuals affected by ‘diabulimia’. 


ARTIC PC- Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care

The aim of the ARTIC PC study is to provide evidence to inform the management of chest infections in Primary Care, in children between the ages of six months and thirteen years.


Liraglutide and the management of Overweight and obesity in people with Schizophrenia: a pilot study. This study will look at the use of a weight loss drug in people with severe mental illness. This is a pilot study to gather data on recruitment, consent, retention, adherence and dropout rates.


A twenty-six week, randomized, open-label, 2-arm parallel group real world pragmatic trial to assess the clinical and health outcomes benefit of transition to Toujeo compared to standard of care insulin, in basal insulin treated patients with uncontrolled type 2 diabetes mellitus, with six-month extension


A study to establish a cohort of people with Type 1 Diabetes and their siblings to further research in this area.

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