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SILAD

Principal Investigator:  Prof Clive Holmes

Study Coordinator: Dr. Jay Amin

The purpose of the study is to find out more information about the role of the immune system in people diagnosed with Lewy Body Dementia and Alzheimer’s Disease and how it may differ from people without a memory disorder. 

The immune system in Alzheimer’s Disease and Lewy Body Dementia has not been well researched but we think that the condition is caused, or made worse, by an overactive immune system which makes it look like an infection is taking place. We want to see if this is the case and if we can prove it we will be in a much better position to develop new treatments. We also think our research could help allow us to develop a blood test for the disease that means Doctors can diagnose the conditions earlier. 

Study staff will ask to visit the participant at home or at MARC. If the participant and their study partner are willing to take part, they will be asked to give consent for participating in the study. 

The study staff will then ask them a series of questions about their health and medications. They will be asked to complete a range of tests to assess memory and thinking ability. 

They will also be asked to complete some brief questionnaires that ask questions about mood. 

The study staff will ask to carry out a blood test (30.5ml, which is approximately 2 tablespoons of blood). 

The study partner will be asked to perform some assessments. These assessments will measure the participant’s mood and level of thinking ability. 

The whole visit will take approximately 2-3 hours to complete.”

Find out more

To find out more please email viv.hopkins@southernhealth.nhs.uk