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ARTIC PC- Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care


The aim of the ARTIC PC study is to provide evidence to inform the management of chest infections in Primary Care, in children between the ages of six months and thirteen years.                  

The study aims to find which children with chest infections benefit from being prescribed antibiotics. Most children who see the doctor with a chest infection currently get antibiotics and the evidence from studies so far suggests that most children do not benefit from having antibiotics. This is the first time in the world anybody has done this particular research. The results will help develop national and, possibly international guidelines for doctors to use in the future.

If you and your child decide to take part in the study:

  • You will be asked some questions about your child’s chest infection.

  • You will be given some study medication for your child – which may be an antibiotic or a dummy antibiotic.

  • You will be given a study diary to fill in until your child is feeling better.

This visit should take about 5 minutes.


  • At the end of the 28 days you will be invited back to see your nurse or GP who will confirm the information you have given and we may ask you your child to perform a breath test which will be done by blowing into a special tube to measure how the lungs are functioning this maybe done 3 times to get an average reading (but only if they are over 6 years old). We will do this both before and after giving your child a medicine to open up the airways.

This visit should take about 15 minutes.

To take part you must meet the following criteria:

  • Aged between 6 months and 12 years.

  • Be presenting with an acute lower respiratory infection (LRTI), defined as an acute cough as the predominant symptom, judged by the doctor or Nurse Practitioner to be infective in origin, lasting <21 days, and with other symptoms or signs localising to the lower tract (sputum).

If you would like to take part or want more information please contact the study lead:

Study Contact: Tricia Monroe


Tel: 02380 475943

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