skip to main content

Previous Studies

Here is a list of studies we have done in the past and any results we may have. These are no longer running but provide a glimpse of the research that has been undertaken within SHFT. 

  • DigiMedSA Multicentre, 8-week, Single-arm, Open-label, Pragmatic Trial to Explore Acceptance and Performance of Using a Digital Medicine System with Healthcare Professionals and Adult Subjects with Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic.
  • TRDA questionnaire study for those with depression that is not responding to treatment.
  • AppRoVEEvaluating the psychotic properties of new measures of responding to distressing voices and other people.
  • DFENDA randomised, double blind, placebo controlled parallel group trial of vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis (DFEND).
  • HWBA questionnaire to provide information about the health and wellbeing of people with serious mental illness (SMI).
  • Culture Free CBTThe aim of this study is to assess the feasibility and acceptability of the intervention using the third wave CBT approach with diverse cultures.
  • STRATIFYA study interested in understanding the connections between certain behaviours such as low motivation, negative emotions, difficulties with attention, alcohol use, eating disorders and unusual experiences regarding Mental illness.
  • EMHePA questionnaire study looking at how patients and mental health service professionals value service quality and outcomes of mental healthcare.
  • LightMind2A study looking at whether self-help books for depression can be helpful.
  • TRD QoLA questionnaire looking at the quality of life for patients and carers affected by depression.
  • TRIumPHTreatment and Recovery in Psychosis is an evaluation of the benefits of a new care pathway for people who have experienced psychosis. Its research aim is to identify if it is possible to implement a psychosis pathway based on principles of early access to services and interventions and whether it is acceptable to patients and staff. The evaluation will be used to improve the services that people receive.
  • UdamoSelf-help apps- do you use them? Are they useful? And how could they be improved?
  • PALSThis project hopes to make people feel more connected in their communities and personal relationships.
  • RADARAiming to understand the long term benefits and drawbacks of reducing, and in some cases, coming off antipsychotic medication.
  • Exploring Unusual FeelingsThis questionnaire study aims to better understand the symptoms of disassociation and to see if these experiences cause psychotic-like experiences.
  • COPeE-support for families and friends of individuals affected by psychosis.
  • Compassion, burnout and self-criticism in mental healthcare professionalsA questionnaire based study with the option of trying out a two week Compassionate Mind Training practices.
  • A Survey of Preferences for the Arts TherapiesA short survey to gain people's opinions about the use of the different genres of Arts Therapies.
  • CLIMBA study to establish the opinions of the public with regards to sharing identified NHS data for clinical purposes and de-identified data for research purposes.
  • Hearing Nasty VoicesA questionnaire study for those who experience derogatory or threatening voices.
  • ARTIC PCInvestigating the use of antibiotics for lower respiratory tract infection in children presenting in primary care.
  • ComPASSIONThis is a short, anonymous, online survey looking to better understand the current level of awareness amongst healthcare professionals of eating disorders in the context of Type 1 diabetes.
  • L.O.S.E WeightLiraglutide and the management of Overweight and obesity in people with Schizophrenia: a pilot study. This study will look at the use of a weight loss drug in people with severe mental illness. This is a pilot study to gather data on recruitment, consent, retention, adherence and dropout rates.
  • RegainA twenty-six week, randomized, open-label, 2-arm parallel group real world pragmatic trial to assess the clinical and health outcomes benefit of transition to Toujeo compared to standard of care insulin, in basal insulin treated patients with uncontrolled type 2 diabetes mellitus, with six-month extension
  • Address 2A study to establish a cohort of people with Type 1 Diabetes and their siblings to further research in this area.
  • Neuro LTCA questionnaire based study which looks to gain a better understanding of factors that predict levels of care and the impact of fatigue for people with Parkinsons Disease, Multiple Sclerosis, Epilepsy, Huntingtons Disease and Motor Neurone Disease and their caregivers.
  • SIGNUMAn observational study that looks to recruit patients that have a history of stroke or at risk of having a stroke and collect genetic and biomarker data linked to recorded data as part of a patient's routine clinical care.
  • StartRightGetting the right classification and treatment from diagnosis in young adults with diabetes.

Thank you to all of our participants for volunteering your time to take part in the research carried out at Southern health NHS Foundation Trust. We truly appreciate you. Without your input the below results would not be possible.


This meta-analysis highlights the importance of the live cell-based assay used in the SINAPPS2/PPiP2 study in NMDAR antibody detection in patients with psychosis.

Paper here.


The AppRoVE study, which investigated the psychotic properties of new measures of responding to distressing voices and other people, has been published and the new questionnaires are available for use. You can find and download the paper and questionnaires from the webpage of the Sussex Voices Clinic here:




You can find a summary of the results produced by our Service User Researcher and PPI Lead Carolyn Asher here.

And a link to the paper below:


National Investigation into suicide in children and young people

The second report from the national investigation into suicide by children and young people is available here: Findings were also included in our NCISH 2018 annual report (page 26-29) -

Our annual reports from the NCISH data are also available from our website -

The end of study report is here.


The TACIT Trial 

You can click here to see the results leaflet from The TACIT Trial.

Page Comments