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Can Anti-TNF drugs reduce Alzheimer's risk? - Clive's comment


A step in the right direction for Alzheimer's Disease research. Prof. Clive Holmes was asked to comment on this latest study into how certain drugs for rheumatoid arthritis reduced risk of Alzheimer's disease.

"The new research "adds further weight to the growing evidence that people who have diseases carrying a systemic inflammatory component have an increased risk of developing Alzheimer's disease," said Clive Holmes, MRCPsych, PhD, of the University of Southampton in England, who was not involved with the study.

"Furthermore, it clearly suggests that drugs that target peripheral inflammation -- in particular, TNF inhibitors -- have the potential to substantially reduce the risk of developing Alzheimer's disease," Holmes told MedPage Today. "Only a large randomized placebo-controlled clinical trial will definitively answer this question, but it is a question that clearly needs answering.""


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