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The London Down Syndrome Consortium (LonDownS): an integrated study of cognition and risk for Alzheimer's Disease in Down Syndrome

Chief Investigator: Dr Andre Strydom, University College London


People with Down Syndrome often differ between one another in their cognitive abilities. Alzheimer’s Disease also occurs more often in individuals with Down Syndrome compared to other individuals. We are collecting data from a large number of individuals with Down Syndrome to investigate some of the reasons that help to explain these differences between individuals with Down Syndrome, and why some people with Down Syndrome develop Alzheimer’s Disease and others do not.

What does the study involve?

Participants will take part in an assessment lasting 2-3 hours, and will also donate a DNA sample

Inclusion Criteria

  • Clinical diagnosis of Down Syndrome
  • Aged 16 or over
  • Native English speakers

Exclusion Criteria

  • Acute health problem


To refer potential participants or to request further information, please contact the research team:


Tel: 02380 475 258